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Accelerating Animal-Free Safety Assessments, Together

About ICCS

The International Collaboration on Cosmetics Safety (ICCS) is focused on advancing the adoption of animal-free science for human and environmental safety assessments of cosmetics and their ingredients through science, education and training, and regulatory engagement.

About ICCS

While animal tests on cosmetics are increasingly banned around the globe, there remain regulatory requirements in different regions of the world that still mandate animal tests, including non-cosmetic related regulations, instead of permitting animal-free new approach methodologies (NAMs). NAMs have been demonstrated as equivalent or better for fulfilling such requirements.


This drives a need for animal testing even where viable NAMs exist. ICCS aims to address this paradox by understanding regulatory needs, supplying sound scientific solutions based on innovative, animal-free approaches for human and environmental health, and addressing education and training needs to collectively build confidence and promote regulatory acceptance.


ICCS will work with all stakeholders, including industry, safety assessors, regulators, and policymakers around the world to share the collective experience of applying NAMs and next-generation risk assessments (NGRA) frameworks to ensure cosmetic safety. In doing so, ICCS will accelerate the transition to global acceptance and use of animal-free science for human and environmental safety assessments for cosmetics.

International Collaboration on Cosmetic Safety
Strategic Priorities

Recent ICCS News

ICCS Announcement
November 22, 2024
Register now! ICCS, in collaboration with Universidade Federal de Goiás Faculty of Pharmacy (FF/UFG) and Tox In Laboratory of Education and Research in In Vitro Toxicology will be presenting the third webinar in the monthly series, “Updates on New Approach Methodologies (NAMs) Applied to Human and Environmental Safety.” This free webinar will be presented in Spanish, on December 18, 14:00 Brasília/Brazil time or 11:00 Mexico City/Mexico and focus on Human Safety. Speakers: Nicole Kleinstreuer, Director of NICEATM, National Institute of Environmental Health Sciences (NIEHS), presenting “(R)evolution in validation” María Laura Gutiérrez, Researcher at Laboratorio de Métodos Alternativos - Facultad de Medicina - UBA/ CONICET, presenting “Advances in Ocular Toxicity: Implementation of Validated Methods and Development of Innovative Approaches” Moderated by: Argel Islas-Robles (Institute for In Vitro Sciences, Inc.) Experts and non-experts on NAMs from academia, industry, and regulatory agencies are welcome to join. 
ICCS Announcement
November 18, 2024
Donna Macmillan, Director, Education and Regulatory Engagement, ICCS has been invited to present, “An introduction to NGRA and selected case studies” as part of the 37th Annual Meeting of the Japanese Society for Alternatives to Animal Experiments (JSAAE).
ICCS Announcement
November 6, 2024
Save the date! ICCS, collaborating with Universidade Federal de Goiás Faculty of Pharmacy (FF/UFG) and Tox In Laboratory of Education and Research in In Vitro Toxicology, will be presenting a free webinar serie, “Updates on New Approach Methodologies (NAMs) Applied to Human and Environmental Safety,” provided in Portuguese or Spanish.
More News

Do you have questions about how ICCS can advance animal-free science around the world?

Contact ICCS
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