ICCS Environmental Health
INTERNATIONAL COLLABORATION ON COSMETICS SAFETY
MAPPING / BACKGROUND RESEARCH
List of Services
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Persistence / Biodegradation: Review of Experimental Approaches and Analytical Methods for Biodegradability / Persistence Assessment of Water-Soluble and Water-Dispersible Polymers
Review of available standard and novel experimental methods, addressing their applicability to assessment of water-soluble and water-dispersible polymer biodegradation; identify gaps and opportunities for research to improve available experimental methods and approaches.
Persistence / Biodegradation: Review of Experimental Approaches and Analytical Methods for Biodegradability / Persistence Assessment of Water-Soluble and Water-Dispersible Polymers
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Persistence / Biodegradation: Review for In Silico Methods for Biodegradation / Persistence Assessment and Their Applicability for Functional Polymers
Review of In Silico methods with focus on their applicability to predict degradation of polymers, considering possible breakdown processes and degradation products; identify gaps and opportunities for research to improve In Silico methods for polymer degradation predictions.
Persistence / Biodegradation: Review for In Silico Methods for Biodegradation / Persistence Assessment and Their Applicability for Functional Polymers
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Aquatic Toxicity: Advances Towards a Harmonized Environmental Safety Analytical Toolbox for Cosmetic Ingredients
Mapping of new environmental NAMs from literature for future regulatory acceptance with machine learning tools: Collection and categorization of literature, method evaluation and database construction, recommendations for regulatory acceptance.
Aquatic Toxicity: Advances Towards a Harmonized Environmental Safety Analytical Toolbox for Cosmetic Ingredients
DEVELOPMENT
List of Services
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Persistence / Biodegradation: International Standard to Calculate Biodegradability of Cosmetic Formulations
Review of existing regulations and approaches, criteria, and standards for assessing the biodegradability of cosmetic, personal care and homecare products.
Persistence / Biodegradation: International Standard to Calculate Biodegradability of Cosmetic Formulations
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Aquatic Toxicity: Development of Internationally Recognised Guidelines for Acute and Chronic Coral Toxicity
Review available test methods related to acute and chronic coral toxicity for different life stages (e.g., larvae, juvenile, adults).
Aquatic Toxicity: Development of Internationally Recognised Guidelines for Acute and Chronic Coral Toxicity
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Persistence / Biodegradation: Symposium on Environmental Degradation and Biodegradation of Water Soluble or Dispersible Polymers
Workshop to develop a roadmap to advance (bio)degradation assessments of water soluble and dispersible polymers.
Persistence / Biodegradation: Symposium on Environmental Degradation and Biodegradation of Water Soluble or Dispersible Polymers
STANDARDIZATION / VALIDATION
List of Services
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Environmental External Exposure: Models to Evaluate direct Release of Cosmetic Ingredients into natural waters (MERCI) Framework with BASF, DSM-Firmenich, and Symrise
Develop tiered exposure modeling framework to evaluate potential environmental exposure of cosmetic ingredients (e.g. UV filters) to marine and freshwater.
Environmental External Exposure: Models to Evaluate direct Release of Cosmetic Ingredients into natural waters (MERCI) Framework with BASF, DSM-Firmenich, and Symrise
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Persistence / Biodegradation: Biodegradation Test Methods Based on Increased Cell Concentrations (ICC) with AISE and Cefic LRI
Focus to make biodegradation assessments more reliable, less variable and more cost-effective; biodegradation assays with increased cell concentrations will be developed and standardized for marine water, freshwater and activated sludge to better represent the sampled environment in the test systems.
Persistence / Biodegradation: Biodegradation Test Methods Based on Increased Cell Concentrations (ICC) with AISE and Cefic LRI
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Mobility: Best Guidance Practices for the Mobility (M) Assessment of Unstable, Reactive, or Ionizable Substances
Recommendations for tests/testing strategies to assess mobility of difficult-to-test substances for which existing test methods might not be fit for purpose.
Mobility: Best Guidance Practices for the Mobility (M) Assessment of Unstable, Reactive, or Ionizable Substances
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Aquatic Toxicity: Cosmetic Ingredient Applicability of the OECD TG 249: RTgill-W1 Fish Cell Line Acute Toxicity Assay
The goal of this project is to explore the suitability of using a cell cytotoxicity assay (i.e., OECD TG 249), in place of In Vivo tests, to assess acute fish toxicity of relevant and representative cosmetic ingredients.
Aquatic Toxicity: Cosmetic Ingredient Applicability of the OECD TG 249: RTgill-W1 Fish Cell Line Acute Toxicity Assay
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Internal Exposure / Bioaccumulation: Expanding the Bioaccumulation NAM Toolbox for Key Cosmetic Ingredient Classes
This project will perform a mapping and gap analysis to perform targeted laboratory testing to advance the bioaccumulation NAM toolbox for key cosmetic ingredient classes.
Internal Exposure / Bioaccumulation: Expanding the Bioaccumulation NAM Toolbox for Key Cosmetic Ingredient Classes