Persistence / Biodegradation: Persistence Assessment Tool with Concawe, Cefic LRI, ECETOC
Objective
Development of a software tool to facilitate the regulatory persistence assessment, including:
- Clear guidance and structure for evaluation of data quality
- Quantitative WoE (qWoE) methodology
- 'Overall persistence’ (Pov) module
- Customization to make the tool globally applicable
- Account for difficult and complex (UVCB) substances
Project Details
Persistence and Biodegradation Working Group
Project Lead:
- Arnaud Boivin, L'Oréal
Collaborators:
- Cefic LRI
- Concawe
- ECETOC
TOOLBOX
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Persistence Assessment Tool
The tool provides a structured and clear methodology to:
- Systematically capture and store information on persistence
- Evaluate data quality
- Carry out a robust and transparent weight of evidence determination
- Assess persistence in line with global regulatory frameworks
Persistence Assessment Tool
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PAT Training Session
The Persistence Assessment Tool (PAT) has been developed by Ricardo, in collaboration with Cefic LRI, Concawe, and ECETOC, in response to the growing interest in the environmental persistence of chemicals, and a need for support to conduct these complex assessments. This training session provides an in-depth look at the use of the tool, including the background and purpose, an overview of features and workflow, and a walkthrough of an example assessment.
PAT Training Session
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Poster: The Persistence Assessment Tool (PAT): Implementing a Methodology for Data Quality Evaluation and Weight of Evidence in Persistence Assessments
Presented at the SETAC EU 2025
Poster: The Persistence Assessment Tool (PAT): Implementing a Methodology for Data Quality Evaluation and Weight of Evidence in Persistence Assessments
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Article: Developing a weight-of-evidence methodology for persistence assessment of substances in the environment
The environmental persistence of a substance plays a key role in determining its exposure to humans and other organisms, making this an important component in the risk assessment and management of chemicals. Regulatory persistence assessments generally involve a comparison of degradation half-lives against threshold criteria for different environmental compartments, typically water, sediment, and soil.
Article: Developing a weight-of-evidence methodology for persistence assessment of substances in the environment