ICCS - International Collaboration on Cosmetics Safety

  Skin Sensitization:  Uncertainty Assessment in the Skin Sensitization NGRA

Objective

The project’s aim is to further build user and stakeholder confidence in the NGRA by developing a plausible, realistic and transparent approach to evaluate NAM-based NGRA uncertainties that informs the appropriateness of the MoE. The objectives are to:

  1. Develop a (semi-)quantitative uncertainty assessment approach to derive a MoE by mapping all potential sources of uncertainty within the NAM-based skin sensitization NGRA
  2. Assess the usefulness of the approach via case studies
  3. Inform and engage the scientific community and stakeholders via dissemination activities

Project Details

Skin Sensitization Working Group

Project Leads:

  • Petra Kern, P&G
  • Nicola Gilmour, Unilever


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